Effect of one session of high intensity interval training (HIIT) on levels of irisin, insulin and insulin resistance index in women with type 2 diabetes
Poster Presentation XML
1alzahra university
2PhD in exercise physiology Faculty of Physical Education and Sport Sciences, Tehran University, Tehran, Iran
Introduction: Irisin is a myokine released from a membrane protein FNDC5 and has positive effects on metabolism. High intensity interval training (HIIT) is also a novel training method which has received most attention in recent years. The aim of this study was to investigate the effect of one session of high intensity interval training (HIIT) on serum irisin, insulin and the insulin resistance index (HOMA-IR) in type 2 diabetes women.
Methodology: In this quasi-experimental study with pretest-posttest design, 23 sedentary women with type 2 diabetes volunteered to participate in the study. After completing the consent form and reviewing the criteria for entering the study (mean age 37 to 50 years old; absence of known physical diseases and ability to perform physical activities) 16 women with type 2 diabetes were selected purposefully. The exercise protocol consisted of 6 bouts of one-minute sprint running with the intensity of 85 to 90 percent of maximum heart rate and 30 seconds of active recovery between sprints. Before and after intervention, serum concentration of irisin, glucose and insulin were measured. Independent t-test was used to analyze data and the level of significance has been considered at p<0.05.
Results: the results of this study showed that after one session of high intensity intermittent activity, the level of irisin increased significantly and insulin levels and insulin resistance index decreased significantly in type 2 diabetes women (p<0.05).
Discussion: The findings of this study indicated that high intensity intermittent exercise could be an effective way to reduce insulin resistance and increase irisin in type 2 diabetic patients.