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The effect of aerobic training on hydrogen peroxide and total antioxidant capacity serum levels and insulin resistance in women with type 2 diabetes
Poster Presentation
Paper ID : 1097-11THCONF
Authors
Department of Sport Science, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran
Abstract
Introduction: Increasing evidence in both experimental and clinical studies suggests that there is a close link between hyperglycemia, oxidative stress and diabetic complications. High blood glucose level determines overproduction of reactive oxygen species by the mitochondria electron transport chain. The present study examined the effect of eight weeks of aerobic training on hydrogen peroxide and total antioxidant capacity (TAC) serum levels and insulin resistance in women with type 2 diabetes.
Methodology: The research was a quasi-experimental design with pre-test and post-test. For this purpose, 25 women with type 2 diabetes mellitus were randomly divided into control group (n = 11, mean age 61 ± 2.89) and experimental (n = 14 with mean age of 59.36 ± 3.22 years). The experimental group performed aerobic training 3 session per week for 8 weeks in three stages: familiarity (45% heart rate reserve), overload (65% heart rate) and load stabilization (65% heart rate reserve). Blood sampling was done 24 hours before and 48 hours after training program. Data were analyzed using dependent and independent t-test (P<0.05).
Results: The findings showed that 8 weeks of aerobic training did not have a significant effect on serum level of hydrogen peroxide and TAC in women with type 2 diabetes (p> 0.05). The results also showed that 8 weeks of aerobic training did not have a significant effect on insulin and fasting blood glucose and also BMI in women with type 2 diabetes (p> 0.05).
Discussion: Based on this findings, it can be concluded that the implementation of eight weeks of aerobic training alone cannot change the hydrogen peroxide and TAC and insulin resistance in women with type 2 diabetes, and it seems that these training, along with the use of medical and nutritional supplements, as well as Increasing the duration of exercises will have the greatest impact on these factors.
Methodology: The research was a quasi-experimental design with pre-test and post-test. For this purpose, 25 women with type 2 diabetes mellitus were randomly divided into control group (n = 11, mean age 61 ± 2.89) and experimental (n = 14 with mean age of 59.36 ± 3.22 years). The experimental group performed aerobic training 3 session per week for 8 weeks in three stages: familiarity (45% heart rate reserve), overload (65% heart rate) and load stabilization (65% heart rate reserve). Blood sampling was done 24 hours before and 48 hours after training program. Data were analyzed using dependent and independent t-test (P<0.05).
Results: The findings showed that 8 weeks of aerobic training did not have a significant effect on serum level of hydrogen peroxide and TAC in women with type 2 diabetes (p> 0.05). The results also showed that 8 weeks of aerobic training did not have a significant effect on insulin and fasting blood glucose and also BMI in women with type 2 diabetes (p> 0.05).
Discussion: Based on this findings, it can be concluded that the implementation of eight weeks of aerobic training alone cannot change the hydrogen peroxide and TAC and insulin resistance in women with type 2 diabetes, and it seems that these training, along with the use of medical and nutritional supplements, as well as Increasing the duration of exercises will have the greatest impact on these factors.
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