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The Effect of High Intensity Interval Training on Serum Levels of Heat Shock Protein 72 and Interleukin 6 in Overweight and Obese Men
Poster Presentation
Paper ID : 1170-11THCONF
Authors
1Professor Assistant in Exercise Physiology
2MsC in exercise physiology. islamic azad university, bojnourd branch
Abstract
Introduction: Adipose tissue expansion is associated with adipocyte dysfunction and increased inflammatory processes. In the obese state, adipose tissue is characterized by an impaired intracellular stress defense system and imbalanced heat shock response. Thus present study examined the effects of High intensity interval training on serum levels of Heat shock protein 72 (HSP72) and Interleukin 6 (IL-6) in overweight and obese men.
Methodology: For this purpose, 20 overweight and obese young men (age: 32.3±2.42 year, BMI: 29.5±4.55 (kg/m2) and PBF: 25.4±4.41 %) randomly divided into 2 groups include control (CON), and High intensity interval training (HIIT). The High Intensity Interval Training was performed 45-60 minutes with 90% heart rate reserve per session, 3 sessions per week3 sessions per week and for 8 weeks. Blood samples were taken 24 hours before and 48 hours after last session training. HSP72 and IL-6 level measured by using ELISA kit. The data were analyzed by SPSS software using independent and paired t-test at significant levels of P<0.05.
Results: The findings showed that 8 weeks of High Intensity Interval Training had a significant decrease in BMI, PBF (P=0.001) and serum levels of IL-6 in overweight and obese young men (P=0.005), also High Intensity Interval Training increased serum levels of HSP72 in overweight and obese men (p=0.015).
Discussion: The basis of these findings can be said that's probably the High Intensity Interval training by reducing PBF and BMI can improve inflammation and HSP72 in overweight and obese men and probably the High Intensity Interval Training can have favorable results in obesity-induced cardiovascular disease.
Methodology: For this purpose, 20 overweight and obese young men (age: 32.3±2.42 year, BMI: 29.5±4.55 (kg/m2) and PBF: 25.4±4.41 %) randomly divided into 2 groups include control (CON), and High intensity interval training (HIIT). The High Intensity Interval Training was performed 45-60 minutes with 90% heart rate reserve per session, 3 sessions per week3 sessions per week and for 8 weeks. Blood samples were taken 24 hours before and 48 hours after last session training. HSP72 and IL-6 level measured by using ELISA kit. The data were analyzed by SPSS software using independent and paired t-test at significant levels of P<0.05.
Results: The findings showed that 8 weeks of High Intensity Interval Training had a significant decrease in BMI, PBF (P=0.001) and serum levels of IL-6 in overweight and obese young men (P=0.005), also High Intensity Interval Training increased serum levels of HSP72 in overweight and obese men (p=0.015).
Discussion: The basis of these findings can be said that's probably the High Intensity Interval training by reducing PBF and BMI can improve inflammation and HSP72 in overweight and obese men and probably the High Intensity Interval Training can have favorable results in obesity-induced cardiovascular disease.
Keywords
High Intensity Interval Training (HIIT); Interleukin-6 (IL-6); Heat Shock Protein 72 (HSP72); Overweight and Obese
Subjects