The effects of time course aerobic training on oxidant and antioxidant status of the liver of male rats
Poster Presentation XML
Paper ID : 1209-11THCONF
1Master of Sport Physiology, Urmia University
2Ph.D. student of Sport Physiology (cardiovascular and respiration) University of Isfahan and lecturer at Qom University
Introduction: Skeletal muscle is the major source of reactive oxygen species produced during sports activities. However, it is possible in certain circumstances other tissues such as the liver, cardiac myocytes, lung or white blood cells ROS production is proven to be involved. Regular exercise leads to an adaptation of the antioxidant systems and regeneration, which increases resistance to oxidative stress . However, the researchers want to answer this question: do regular exercises intervention may be due to its antioxidant effects of the liver tissue support?
Methodology: In this study 32 male rats of 150 g after two months engaged in aerobic exercise schedule, six days a week for ten weeks at 10 m /10 increasingly beginning and in the end of the tenth week each two weeks time and speed are were added to comply overload. Sampling stage before the first training session in the first week liver tissue and were collected. The second stage of the sampling after the fourth week of the last training session. From the fifth week until the end of the eighth week, workouts, speed 15 m / min continued. The third step taken in the last session of the eighth week, similar to the second stage sampling was repeated. And finally the fourth stage sampling period in the last training session, the same process was repeated. Subjects liver tissue carefully removed and checked for the amount of oxidation in the liver and blood was in possession of the relevant laboratories.
Results: An aerobic endurance training period (4, 8, 10 weeks) increases the level of oxidative stress indexes in the rat liver, also increases the measure of antioxidant enzymes in the rat liver, but it does not cause a significant change in the level of the antioxidant enzymes activity in the liver.
Discussion: The results showed that while stress (intensity and duration of training sessions) not severe and moderate manner consistent with respect for the principle of overload or turns the volume balance training can be adjusted by increasing the action of enzymes and damage to body tissues not entered.