Effect of 12 week high-intensity interval and moderate-intensity continuous training on IL-4 and IL-2 in obese women
Poster Presentation XML
1university ardakan
2ardakan universitiy
3ardakan university
Introduction: Substantial literature has emerged that shows that overweight and obesity are major causes of co-morbidities, including T2DM, cardiovascular diseases, various cancers, and other health problems, which can lead to further morbidity and mortality. Obesity is a chronic disease of multifactorial origin that develops from the interaction of social, behavioral, psychological, metabolic, cellular, and molecular factor. Fundamentally, obesity is the result of excessive energy consumption compared with the energy expended. Physical exercise is an important strategy for reduction of inflammatory established process. The aim of this study was to evaluate the effect of 12 weeks of two exercise training programs in the inflammatory profile in obesity women.
Methodology: Sixty women (51.26±6.23 years; 176.14±4.31 cm; 89.41±10.58 kg) were divided into two groups for training on a treadmill: continuous at 75% maximum heart rate (HRmax) 4 times a week (CONT) and 3×4 min (high intensity interval training, HIIT) at 90% HRmax 3 times a week. IL4 and IL-2 levels were analyzed by enzyme-linked immunosorbent assay. Data collected using independent T test and ANOVA at the significant level of p<0.05.
Results: After 12 weeks of training blood concentrations of IL-4 and IL-2 decreased in the HIIT group (P=0.043 and P=0.033, respectively). There was a trend towards decreased body weight and body mass index (BMI) after CONT and HIIT (P=0.047 and P=0.037, respectively).
Discussion: Thus, based on the results of this study it can be stated that 12 weeks HIIT as well as CONT exercises training program promotes changes in inflammatory profile in obesity women.