The effect of regular aerobic training on Ghrelin level in obese women
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1دانشگاه مراغه
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Abstract
Introduction: Ghrelin are hormones involved in obesity. Ghrelin, a 28-amino acid peptide recently isolated from the human and rat stomach, is also present in human and rat pancreatic alpha-cells. It is also recognized as a novel player in the gut-brain regulation of growth hormone and energy balance 3. The molecule has been shown to be a growth hormone (GH) secretagogue that stimulates an increase in blood glucose. Ghrelin has a potent effect on eating behavior, causing an increase in hunger2 and plays a key role in the central regulation of feeding 6. It has been suggested that the stomach is a major source of circulating Ghrelin in humans. Interestingly, Ghrelin levels are significantly altered during acute and chronic aberration in nutritional status. Thus Ghrelin levels are low in simple obesity but increase after weight loss. The aim of this study of the Effect of 8 weeks of aerobic training on Ghrelin level in obese women.
Methodology: Participants were 40 obese women which randomly assigned into control and experimental groups. The experimental group performed 8 weeks of aerobic exercise and the control group remained sedentary. Blood samples were collected 24 hours before the first session and 48 hours after the last session (participants were fasting). And The Ghrelin and HDL, LDL, TG ,TC were measured. Data were analyzed by SPSS software (version 18).
Results: There was significant difference between indexes of, HDL, LDL, TG and TC in control and aerobic exercise groups. There were no significant difference in Ghrelin indexes between both groups after 8 weeks of aerobic exercise (p>0.05).
Discussion: It is unlikely that the aerobic exercise intensity or obesity/thinness would be the only effective factors on appetite in women. It seems moderate-intensity exercise would be preferential in weight loss programs because of its higher energy expenditure. Additionally, it is expected that moderate intensity exercise would give better results also in body weight gain programs due to smaller increases in a feeling of hunger in thin individuals with low-intensity exercise. However, since true energy intake was not measured in this study (and considering lack of evidence in this area), longitudinal studies are needed to throw more light on the subject.
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