- |
-
The effect of training in hypoxia conditions on HIF-1 level and changes of PGC-1α in elite endurance runners
Poster Presentation
Paper ID : 1577-11THCONF
Authors
1manager in sport organization of Tehran municipality
2Associated professor of University of Tehran
Abstract
Introduction: The aim of this study was to investigate The effect of training in hypoxia conditions on HIF-1 level and Changes of PGC-1α in elite endurance runners.
Methodology: In this semi experimental study, the 8 men of the national team's runners took part in the research. The training program was the same for all based on the existing training practices, continuous, alternative, aerobic and resistance training. Runners from 15 to 18 sessions a week and for five weeks of living in altitude, training at altitude and at sea levels in training. blood sampling at the pre-test (basal level of normoxia), posttest 1 (pre-hypoxia), post-test 2 (post-hypoxia) and post-test 3 (after sea level) taken in four times.
Results: The results of the pre-test (basal level of normoxia), posttest 1 (pre-hypoxia), post-test 2 (post-hypoxia) and post-test 3 (after sea level) in four measurement times showed that there was a significant difference in The expression of the HIF-1 level and PGC-1α between the measurement times (P=0.001). The results showed There was no significant difference between the baseline level with pre-test and pre-test with sea level in HIF-1 values, but there was a significant difference between the other measurement times (P=0.001). Also, there was no significant difference between the pre-test with post -test in PGC-1α values, but there was a significant difference between the other measurement times (P=0.001).
Discussion: According to the results of this study, it seems to training in hypoxia can have a positive effect on HIF-1α and PGC-1α levels possibly performance improvement in athletic endurance.
Methodology: In this semi experimental study, the 8 men of the national team's runners took part in the research. The training program was the same for all based on the existing training practices, continuous, alternative, aerobic and resistance training. Runners from 15 to 18 sessions a week and for five weeks of living in altitude, training at altitude and at sea levels in training. blood sampling at the pre-test (basal level of normoxia), posttest 1 (pre-hypoxia), post-test 2 (post-hypoxia) and post-test 3 (after sea level) taken in four times.
Results: The results of the pre-test (basal level of normoxia), posttest 1 (pre-hypoxia), post-test 2 (post-hypoxia) and post-test 3 (after sea level) in four measurement times showed that there was a significant difference in The expression of the HIF-1 level and PGC-1α between the measurement times (P=0.001). The results showed There was no significant difference between the baseline level with pre-test and pre-test with sea level in HIF-1 values, but there was a significant difference between the other measurement times (P=0.001). Also, there was no significant difference between the pre-test with post -test in PGC-1α values, but there was a significant difference between the other measurement times (P=0.001).
Discussion: According to the results of this study, it seems to training in hypoxia can have a positive effect on HIF-1α and PGC-1α levels possibly performance improvement in athletic endurance.
Keywords
Subjects