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Effect of six weeks aerobic training with of jujubes extract administration on the level of plasma Irisin in myocard infration rats
Poster Presentation
Paper ID : 1667-11THCONF
Authors
1کارشناسی ارشد، دانشگاه بیرجند
2University of Birjand
3عضو هیئت علمی دانشکده تربیت بدنی دانشگاه بیرجند
4عضو هیئت علمی دانشکده کشاورزی دانشگاهبیرجند
5دانشجوی دکترا دانشگاه بوعلی
6ma student azad university of karaj
Abstract
Introduction: Myocard infarction can be considered as one of the causes of death and disability in the world. Moreover, Irisin, as a new myokine, that secreted by the heart and muscle, is a biological marker for heart attack. Cardiac rehabilitation programs designed to prevent secondary outbreaks, including preventing subsequent consequences and reducing cardiac disease progression. Exercises are part of these rehab programs for patients with heart attacks. The purpose of this study was to investigate the effect of continuous and intermittent aerobic exercise with jujube extracts on male Wistar rats suffering from myocardial infarction.
Methodology: For this purpose, 36 male Wistar rats suffered from heart attack selected and divided in 6 equal groups (each group of 6 mice): 1. Control group; 2. Jujube extract group (400 mg / kg body weight); 3. Intermittent aerobic exercise (55-60% VO2max), 4. Continuous aerobic exercise (70-75% VO2max), 5. Intermittent exercises and jujube extracts, and 6 Continuing exercises and jujube extracts. Exercise protocol includes: 1. intermittent aerobic exercise training including 5 cycles of 4 minutes at 15 km / h and 5 cycles of 4 minutes at a speed of 23 km / h. The continuous aerobic exercise training included 40 minutes of running at a speeds of 10 Km / h in the first week and at the same time but at an intensity of 16 km / h in the last week. The consumption of jujube extracts 400 mg / kg per day was given by gavage. Blood sampling was performed after six weeks of exercise training and jujube extracts. Plasma Irisin content was measured by ELISA method. One-way ANOVA was used to analyze the data and the significance level was considered as p<0.05.
Results: Results showed that continuous and intermittent aerobic exercise and jujube extracts alone and in combination did not significantly change the level of plasma Irisin. But Irisin showed a tendency to increase in the intermittent and continuous aerobic exercise groups.
Discussion: It is possible that this increase is due to changes in the body composition and the increase in muscle tissue to facilitate and increase the levels of myopic infections such as PGC1α, FNDC5 and Irisin.
Methodology: For this purpose, 36 male Wistar rats suffered from heart attack selected and divided in 6 equal groups (each group of 6 mice): 1. Control group; 2. Jujube extract group (400 mg / kg body weight); 3. Intermittent aerobic exercise (55-60% VO2max), 4. Continuous aerobic exercise (70-75% VO2max), 5. Intermittent exercises and jujube extracts, and 6 Continuing exercises and jujube extracts. Exercise protocol includes: 1. intermittent aerobic exercise training including 5 cycles of 4 minutes at 15 km / h and 5 cycles of 4 minutes at a speed of 23 km / h. The continuous aerobic exercise training included 40 minutes of running at a speeds of 10 Km / h in the first week and at the same time but at an intensity of 16 km / h in the last week. The consumption of jujube extracts 400 mg / kg per day was given by gavage. Blood sampling was performed after six weeks of exercise training and jujube extracts. Plasma Irisin content was measured by ELISA method. One-way ANOVA was used to analyze the data and the significance level was considered as p<0.05.
Results: Results showed that continuous and intermittent aerobic exercise and jujube extracts alone and in combination did not significantly change the level of plasma Irisin. But Irisin showed a tendency to increase in the intermittent and continuous aerobic exercise groups.
Discussion: It is possible that this increase is due to changes in the body composition and the increase in muscle tissue to facilitate and increase the levels of myopic infections such as PGC1α, FNDC5 and Irisin.
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