Effects of 8 weeks of hypoxic and normoxic resistance training and hypoxic exposure on vascular structure in overweight men
Oral Presentation XML
1Sudent of PHD Razi Universal
2Associate Professor of Physical Education at Razi University of Kermanshah
3استادیار دانشکده تربیت بدنی دانشگاه رازی کرمانشاه
Introduction: The aim of this study was to evaluate the effect of 8 weeks of hypoxic and normoxic resistance training and hypoxic exposure on intima-media thickness (IMT) in femoral artery in overweight men. IMT is an anatomic structural measure of subclinical atherosclerosis. IMT have been associated with cardiovascular risk factors and cardiovascular events. Wall thickness has been used in peripheral conduit arteries to reflect arterial remodeling, a process that may depend on exercise-mediated changes in systemic hemodynamics and arterial shear stress. Previous studies reported important differences in the impact of different exercise modalities on systemic changes in shear stress during bouts of exercise. Studies are needed to refine the best mode of exercise training that will decrease IMT.
Methodology: Thirty overweight men with the mean age of 19.8±1.13 and the mean weight 85.2±6.53 participated in this study voluntarily and randomly allocated to hypoxic exposure, hypoxic resistance training, or normoxic resistance training group. Resistance training involved of squat and lunges exercises. Training was carried out 3 days/week for 8 weeks. Before and after the interventions, femoral artery IMT was measured from the images derived from an ultrasound machine.
Results: Results of the present study showed that IMT decreased after all protocols (p<0.05); and significant different was observed for the IMT in groups (p<0.05).
Discussion: Our findings showed that exercise has impact on remodeling of femoral artery in overweight men. These findings suggest that IMT, a vascular characteristic associated previously with atherosclerosis, can decrease to training program. Previous studies have indicated resistance exercise and hypoxia caused the increase arterial shear stress and consequent endothelial nitric oxide production. They have been showed that repetitive increases in shear induce endothelium-mediated changes in artery size and conseqent arterial architecture. Atherosclerosis is a complex disease and may have multiple pathways. Femoral artery IMT may be independent stage in these pathways that may be decrease via training program.