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Effect of aqueous extract of Cinnamomum Zeylanicum on ALT, AST and ALP concentration after delayed onset muscle soreness in active men
Poster Presentation
Paper ID : 1731-11THCONF
Authors
coach
Abstract
Introduction: The purpose of present study was investigate the effect of aqueous extract of Cinnamomum Zeylanicum on ALT, AST and ALP concentration after Delayed onset muscle soreness in active men.
Methodology: 28 men (18-24 years) in double-blind study divided into four groups: Cinnamomum extract group (Cin, n=7), Ibuprofen group (Ibo, n=7), Placebo group (n=7), positive control group (50% of Ibuprofen +50% of aqueous extract, Ibo+Cin, n=7) and one week before starting to exercise, they consumed supplement in form of capsule every 12 hours. Exercise protocol included four sets of eccentric contraction of hamstring muscle in nondominant foot with 110% of 1RM. The blood samples were collected before exercise, after exercise and 24, 48 and 72 hours recovery from exercise. All data were normalized by a Kolmogorov-Smirnov (k-s) test. Data Analyzes of within group comparison using one way repeated measure ANOVA for ALT, AST and ALP in done and for comparing the between group changes (ALT, AST and ALP) was used repeated measure ANOVA with between group factor. If significant interaction of time and different groups was observed LSD test was used. Statistical significance was set at P<0.05.
Results: The results showed that eccentric exercise induced cell damage and enhance of liver enzymes in placebo group. The Cinnamomum extract caused significant decrease in ALT and AST levels but no significant changes observed in ALP levels. also, Ibuprofen did not cause the significant reduction in ALP, AST, ALT levels.
Discussion: Therefore, the Cinnamomum extract improves athletes performance and decrease the cell damage due to delayed onset muscle soreness.
Methodology: 28 men (18-24 years) in double-blind study divided into four groups: Cinnamomum extract group (Cin, n=7), Ibuprofen group (Ibo, n=7), Placebo group (n=7), positive control group (50% of Ibuprofen +50% of aqueous extract, Ibo+Cin, n=7) and one week before starting to exercise, they consumed supplement in form of capsule every 12 hours. Exercise protocol included four sets of eccentric contraction of hamstring muscle in nondominant foot with 110% of 1RM. The blood samples were collected before exercise, after exercise and 24, 48 and 72 hours recovery from exercise. All data were normalized by a Kolmogorov-Smirnov (k-s) test. Data Analyzes of within group comparison using one way repeated measure ANOVA for ALT, AST and ALP in done and for comparing the between group changes (ALT, AST and ALP) was used repeated measure ANOVA with between group factor. If significant interaction of time and different groups was observed LSD test was used. Statistical significance was set at P<0.05.
Results: The results showed that eccentric exercise induced cell damage and enhance of liver enzymes in placebo group. The Cinnamomum extract caused significant decrease in ALT and AST levels but no significant changes observed in ALP levels. also, Ibuprofen did not cause the significant reduction in ALP, AST, ALT levels.
Discussion: Therefore, the Cinnamomum extract improves athletes performance and decrease the cell damage due to delayed onset muscle soreness.
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