The effect of 8 weeks hypoxia and normoxia on irisin levels and insulin resistance index in overweight men
Poster Presentation XML
1Masters student razi University
2استاد یار دانشگاه رازی
3Assistant Professor, Faculty of Exercise Physiology and Sports Nutrition, Razi University, Kermanshah, Iran
Introduction: Irisin is a new myokine that exerts its positive effects via increasing energy expenditure. The purpose of this study was to determine the effect of 8 weeks aerobic training in hypoxia and normoxia conditions on serum irisin level and insulin resistance change in obese men.
Methodology: In this study, 14 overweight subjects with an average age (23.86 ± 4.14), height (175.5 ± 4.96 cm) were randomly divided to two groups: hypoxia (15% oxygen concentration) and normoxia (normal conditions). The program involved training with 60% of the maximum per-oxygen consumption for 3 sessions per week, 50 minutes per session lasting for 8 consecutive weeks. The gas analyzer was used to determine the maximum oxygen consumption of the subjects. 24 hours before and after the participation in the study, blood samples were taken from subjects in fasting state for measuring blood factors. To evaluate intra and between groups’ comparison, paired and independent student T test were used. For all statistical comparisons, the level of significance was considered at P≤0.05.
Results: Eight weeks of aerobic training in the hypoxia group produced a significant increase in serum irisin levels (P= 0.00), but no changes were observed in the normoxia group (P = 0.07). Changes in insulin resistance after the training period in the hypoxia group (P=0.73) and in the normoxia group (P=0.11) were not significant. Conclusion: 8 weeks of aerobic training had an effect on serum irisin levels and insulin resistance. Changes in the irisin and insulin resistance in the hypoxia groups versus of normoxia was more.
Discussion: Therefore, it seems that the environmental conditions of the training cause a difference in the rate of change in the two groups.