The Effect of a 12-Week High Intensity Interval versus Continuous Endurance Training with Intensities Equivalent to Fatmax or Anaerobic Threshold on Irisin and Preptin Changes in Prediabetes Patients
Oral Presentation XML
Paper ID : 1937-11THCONF
1دانشکده تربیت بدنی دانشگاه گیلان
2دانشکده تربیت بدنی و علوم ورزشی دانشگاه گیلان.
3Assistant Professor of Exercise Physiology, Sport Sciences Research Institute of Iran
Introduction: The aim of this study was to examine the effects of a 12-week high intensity interval exercise training represents an effective interventional strategy to the prevention, care and management of type 2 diabetes (T2D) and pre-diabetes patients and training (HIIT) or isocaloric continuous endurance training (CET) on insulin resistance indexes and Irisin and Preptin changes in pre-diabetes patients.
Methodology: Thirty-two pre-diabetic male patients (age=38.7±4; body mass index=26.9±1.4 kg*m-2; body fat=26.1±2.5%; V̇O2peak=2.49±0.22 L*min-1) were randomized into three training groups (N=8) which were matched based on their energy expenditure (EE) during and post-exercise activation through excess post-exercise oxygen consumption (EPOC): (a) HIIT (10×60s at 90% peak oxygen uptake [V̇O2peak], 1;1 work to recovery at 50W), (b) Continuous endurance training at intensity equivalent to maximal fat oxidation (Fatmax) (CETFAT) (pedaling as long as individual can apply EE equivalent to a HIIT session [E≈HIIT]), (c) Continuous endurance training at intensity equivalent to anaerobic threshold (CETAT) (E≈HIIT), and (d) The control group (CON) continued to perform their daily activity.
Results: In post-test, blood glucose levels were significantly (p<0.05) lower in the HIIT group when compared to CETAT group. The effectiveness of exercise training on insulin resistance index was 35%, 28% and 37% in CETFAT, CETAT and HIIT groups, respectively. The Irisin concentrations in HIIT and CETAT groups were significantly (p<0.05) decreased when compared to the pre-training values. Also, HIIT and CETFAT resulted in significant (p<0.05) changes in preptin concentration compared to pretest.
Discussion: This study demonstrated that both HIIT and CETFAT protocols had similar effects on insulin resistance index in pre-diabetes patients. Also, the intensity and type of exercise were effective in changing irisin and preptin concentrations.