The effect of twelve weeks of average aerobic training on IL-33 serum levels of type 2 diabetic patients
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Paper ID : 1956-11THCONF
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علوم تربیتی دانشگاه فرهنگیان تهران ایران
Abstract
Introduction: The human body is always influenced by an environment of microbial agents’ infection. These microorganisms have the potential for uncontrolled proliferation, pathological damage and eventually destroy their host Physical activities can change many components and function of the immune system. The aim of this study was to evaluate the effects of twelve weeks of average aerobic exercise on serum levels of IL-33 in patients with type 2 diabetes.
Methodology: The subjects of this study were diabetic patients attending to diabetes clinic in Karaj. They were invited by target and 60 diabetic patients aged 35 to 55 years, were chosen and divided randomly into two groups. This study was performed with equivalent of 50 to 55% vo2max aerobic exercise. Blood samples were collected one day before and one day after practice and serum levels of IL-33 in the laboratory using ELISA kits of bendermed Canada.
Results: The results showed a significant decrease in IL-33 levels after exercise (P> 0.01). These results indicated that 8 weeks of aerobic training provide significantly reduced interleukin-33 inflammatory indexes among diabetics. Our results indicated that the diabetic patient's immune system to be changed and improved with aerobic exercise and cause to improve immune function and inflammation and reduce the levels of IL-33. The changes can reduce insulin use and improve diabetes disease. The results showed a significant decrease of IL-33 after 12 weeks.
Discussion: As a result it can be concluded that aerobic exercise reduces levels of inflammation and relieve disease of diabetes. However, the effects of exercise and sports on various variables need to be researched further on inflammatory and immune systems.
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